Cell cycle control of DNA joint molecule resolution
نویسندگان
چکیده
منابع مشابه
Cell cycle control of chromosomal DNA replication.
Accurate replication and segregation of chromosomal DNA is essential for high-fidelity transmission of genetic information from generation to generation. Eukaryotic cells typically replicate by first duplicating their chromosomes during the S phase followed by their segregation between two daughter cells during the M phase. Over recent years, advances in our understanding of this process at the...
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DNA double strand breaks (DSBs) elicit prompt activation of DNA damage response (DDR), which arrests cell-cycle either in G1/S or G2/M in order to avoid entering S and M phase with damaged DNAs. Since mammalian tissues contain both proliferating and quiescent cells, there might be fundamental difference in DDR between proliferating and quiescent cells (or G0-arrested). To investigate these diff...
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Faithful chromosome segregation in meiosis is crucial to form viable, healthy offspring and in most species, it requires programmed recombination between homologous chromosomes. In fission yeast, meiotic recombination is initiated by Rec12 (Spo11 homolog) and generates single Holliday junction (HJ) intermediates, which are resolved by the Mus81-Eme1 endonuclease to generate crossovers and there...
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Aspects of the regulation of DNA replication and mitosis have been studied using a cell-free extract of Xenopus eggs. The extract is characterized by repeated cycles of DNA replication and mitosis, which are accompanied by periodic synthesis and degradation of cyclins as well as fluctuations in the level of Histone H1 kinase activity. DNA replication in this system is dependent upon the formati...
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Clustering web documents has numerous applications, such as aggregating news articles into meaningful events, detecting trends and hot topics on the Web, preserving diversity in search results, etc. At the same time, the importance of named entities and, in particular, the ability to recognize them and to solve the associated co-reference resolution problem are widely recognised as key enabling...
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2016
ISSN: 0955-0674
DOI: 10.1016/j.ceb.2016.02.018